Q-omics provides the consensus-scored MT-TK profile across patient tissues and cancer cell-line models. MT-TK expression is associated with patient survival in 3 of 34 cancer types, with the highest sampling consensus in STAD. Additionally, MT-TK RNA expression shows 148 significant gene co-expression associations, with the highest sampling consensus in OV. Together, these results highlight STAD, and OV as cancer lineages where MT-TK shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MT-TK survival associations across molecular data types. MT-TK RNA expression shows survival associations in the most cancer types (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MT-TK data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	3	OV (54)	view →

This table ranks reproducible MT-TK RNA expression–survival associations across cancer types. High MT-TK expression shows unfavorable associations in STAD, OV and LGG. The STAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify STAD as the clearest survival context for MT-TK RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Tertile	All	0.022	0.731	<.001	54	view →
OV	OS	Tertile	All	0.361	0.841	.038	54	view →
LGG	OS	Tertile	All	0.300	0.830	.034	9	view →

Pink = unfavorable, green = favorable. all 3 lineages →

MT-TK-STAD (OS)

Kaplan–Meier survival curve for MT-TK RNA expression in STAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MT-TK in patient tissues and cancer cell lines. In patient samples, MT-TK shows the broadest associations at the RNA and protein expression levels, with OV recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	148	OV (46)	view →
Mutation	71	BRCA (47)	view →