MT-TK

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MT-TK RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated MT-TK data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher MT-TK RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MT-TK expression acts as an unfavorable survival marker.

STAD, OV, and LGG are the cancer types where MT-TK RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADOSTertileAll0.0220.731<.00154view →
OVOSTertileAll0.3610.841.03854view →
LGGOSTertileAll0.3000.830.0349view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration