Across TCGA patient cohorts, MT-TI RNA expression is significantly associated with the go_rna of many other GO terms, with 4,811 significant associations in total. LGG shows the largest number of these associations.

The most reproducible MT-TI-associated GO terms across cancer lineages are Proton transmembrane transport, Oxidative phosphorylation, and Single fertilization. Each is linked with MT-TI in more than 9 cancer types. Because this analysis shows association rather than direction, both MT-TI-to-partner and partner-to-MT-TI results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TI→partner) and Y-score (partner→MT-TI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	Proton transmembrane transport →	+0.016	+0.508	<.001	<.001	3	10
LUSC	Oxidative phosphorylation →	+0.017	+0.223	.003	.002	2	10
ESCA	Single fertilization →	+0.018	+0.346	.002	<.001	3	9
COAD	NADH dehydrogenase complex assembly →	+0.016	+0.626	<.001	<.001	3	8
STAD	Protein maturation by [4Fe-4S] cluster transfer →	+0.037	+0.689	<.001	<.001	3	8
LAML	[2Fe-2S] cluster assembly →	+0.042	+1.640	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,811 associations by consensus.

Exploration

MT-TI survival (RNA) · tumor vs normal (RNA) · all MT-TI data types