Across TCGA patient cohorts, MT-TF RNA expression is significantly associated with the go_rna of many other GO terms, with 6,805 significant associations in total. LGG shows the largest number of these associations.

The most reproducible MT-TF-associated GO terms across cancer lineages are Oxidative phosphorylation, Mitochondrial electron transport, NADH to ubiquinone, and Respiratory electron transport chain. Each is linked with MT-TF in more than 18 cancer types. Because this analysis shows association rather than direction, both MT-TF-to-partner and partner-to-MT-TF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TF→partner) and Y-score (partner→MT-TF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Oxidative phosphorylation →	+0.062	+0.721	<.001	<.001	3	19
ESCA	Mitochondrial electron transport, NADH to ubiquinone →	+0.049	+1.110	<.001	<.001	2	18
STAD	Respiratory electron transport chain →	+0.059	+0.874	<.001	<.001	3	16
STAD	ATP synthesis coupled electron transport →	+0.064	+0.794	<.001	<.001	3	16
STAD	Electron transport chain →	+0.051	+0.699	<.001	<.001	3	16
KICH	Meiotic chromosome condensation →	-0.094	-2.295	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,805 associations by consensus.

Exploration

MT-TF survival (RNA) · tumor vs normal (RNA) · all MT-TF data types