Across TCGA patient cohorts, MT-TE RNA expression is significantly associated with the go_rna of many other GO terms, with 6,379 significant associations in total. LGG shows the largest number of these associations.

The most reproducible MT-TE-associated GO terms across cancer lineages are Mitotic spindle elongation, Positive regulation of chromosome condensation, and Spindle midzone assembly. Each is linked with MT-TE in more than 15 cancer types. Because this analysis shows association rather than direction, both MT-TE-to-partner and partner-to-MT-TE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-TE→partner) and Y-score (partner→MT-TE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
MESO	Mitotic spindle elongation →	-0.104	-0.938	<.001	<.001	3	16
DLBC	Positive regulation of chromosome condensation →	-0.142	-1.377	<.001	<.001	2	16
MESO	Spindle midzone assembly →	-0.084	-0.807	<.001	<.001	3	15
STAD	Positive regulation of chromosome segregation →	-0.066	-0.728	<.001	<.001	3	15
DLBC	Mitotic chromosome condensation →	-0.102	-1.176	<.001	.002	2	15
DLBC	Meiotic chromosome condensation →	-0.147	-1.222	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,379 associations by consensus.

Exploration

MT-TE survival (RNA) · tumor vs normal (RNA) · all MT-TE data types