Across TCGA cell cohorts, MT-CO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,936 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MT-CO1-associated GO terms across cancer lineages are Purine deoxyribonucleoside monophosphate biosynthetic process, DAMP biosynthetic process, and Maintenance of unfolded protein. Each is linked with MT-CO1 in more than 10 cancer types. Because this analysis shows association rather than direction, both MT-CO1-to-partner and partner-to-MT-CO1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MT-CO1→partner) and Y-score (partner→MT-CO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Purine deoxyribonucleoside monophosphate biosynthetic process →	-0.137	-1.165	<.001	.007	3	11
URINARY_TRACT	DAMP biosynthetic process →	-0.137	-1.165	<.001	.007	3	11
OVARY	Maintenance of unfolded protein →	+0.141	+1.071	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of nuclear division →	-0.161	-1.657	.001	.001	3	10
OVARY	Attachment of spindle microtubules to kinetochore →	-0.089	-0.975	.004	.001	3	9
BONE	Body fluid secretion →	+0.114	+0.869	.005	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,936 associations by consensus.

Exploration

MT-CO1 survival (RNA) · tumor vs normal (RNA) · all MT-CO1 data types