MST1R

Across TCGA cell cohorts, MST1R RNA expression is significantly associated with the go_rna of many other GO terms, with 4,032 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible MST1R-associated GO terms across cancer lineages are Macrophage colony-stimulating factor signaling pathway, Maintenance of blood-brain barrier, and Cellular response to macrophage colony-stimulating factor stimulus. Each is linked with MST1R in more than 13 cancer types. Because this analysis shows association rather than direction, both MST1R-to-partner and partner-to-MST1R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macrophage colony-stimulating factor signaling pathway grouped by MST1R-low versus MST1R-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MST1R→partner) and Y-score (partner→MST1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Macrophage colony-stimulating factor signaling pathway →	+1.544	+4.031	<.001	<.001	3	14
STOMACH	Maintenance of blood-brain barrier →	+0.235	+3.559	<.001	<.001	3	11
OVARY	Cellular response to macrophage colony-stimulating factor stimulus →	+1.221	+2.127	<.001	<.001	3	11
LUNG_SCLC	Mammary gland duct morphogenesis →	+0.282	+1.899	<.001	<.001	3	11
STOMACH	Regulation of cardiac muscle cell action potential →	+0.193	+3.394	<.001	<.001	3	11
STOMACH	Regulation of ventricular cardiac muscle cell action potential →	+0.234	+2.937	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,032 associations by consensus.

Macrophage colony-stimulating factor signaling pathway by MST1R expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →