MST1R

Across TCGA pan-cancer cohorts, MST1R RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated MST1R data layer compared with 9 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher MST1R RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated MST1R expression acts as an unfavorable survival marker, although some lineages such as BLCA and UCEC show a favorable association.

BLCA, ACC, and UCEC are the cancer types where MST1R RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.515	0.284	<.001	84	view →
ACC	OS	Median	II,III,IV	0.344	0.866	<.001	62	view →
UCEC	DFS	Quartile	II,III,IV	0.751	0.399	.002	36	view →
LUSC	DFS	Median	All	0.719	0.793	.008	33	view →
LIHC	OS	Quartile	II,III,IV	0.441	0.843	<.001	31	view →
UCS	DFS	Tertile	IV	0.857	0.237	.024	24	view →
LAML	DFS	Tertile	All	0.334	0.579	.009	24	view →
LUAD	DFS	Median	II,III,IV	0.174	0.370	.016	21	view →
PAAD	DFS	Quartile	All	0.269	0.568	.002	18	view →
UVM	OS	Tertile	All	0.953	0.722	.009	18	view →
STAD	DFS	Median	IV	0.199	0.644	.010	18	view →
THYM	OS	Median	All	0.764	0.983	.014	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

MST1R–BLCA (DFS)

Open the BLCA breakdown →