Across TCGA patient cohorts, MS4A18 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MS4A18-associated genes across cancer lineages are MIR133B, MIR1258, and FAM243A. Each is linked with MS4A18 in more than 1 cancer types. Because this analysis shows association rather than direction, both MS4A18-to-partner and partner-to-MS4A18 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MS4A18→partner) and Y-score (partner→MS4A18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR133B →	+0.356	+8.066	<.001	.007	3	1
UCEC	MIR1258 →	+0.509	+8.066	<.001	.007	3	1
UCEC	FAM243A →	+0.069	+8.066	<.001	.007	3	1
UCEC	RNU7-95P →	+0.562	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

MS4A18 survival (RNA) · tumor vs normal (RNA) · all MS4A18 data types