MRPS33

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MRPS33 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,316 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible MRPS33-associated GO terms across cancer lineages are tRNA dihydrouridine synthesis, Mitochondrial respirasome assembly, and Cell motility involved in cerebral cortex radial glia guided migration. Each is linked with MRPS33 in more than 10 cancer types. Because this analysis shows association rather than direction, both MRPS33-to-partner and partner-to-MRPS33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA dihydrouridine synthesis grouped by MRPS33-low versus MRPS33-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS33→partner) and Y-score (partner→MRPS33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYtRNA dihydrouridine synthesis →+0.091+0.586<.001<.001311
BLOOD_LeukemiaMitochondrial respirasome assembly →+0.108+0.548<.001<.001310
OESOPHAGUSCell motility involved in cerebral cortex radial glia guided migration →-0.149-0.558.003.00439
BREASTProtein insertion into mitochondrial membrane →+0.090+0.791<.001<.00138
UPPER_AERODIGESTIVE_TRACTProton-transporting two-sector ATPase complex assembly →+0.089+0.725.002.00138
BONEPositive regulation of isotype switching to IgG isotypes →+0.137+0.627.001.00638
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,316 associations by consensus.

tRNA dihydrouridine synthesis by MRPS33 expression — KIDNEY

Box plot of tRNA dihydrouridine synthesis in MRPS33-low vs MRPS33-high samples in KIDNEY.

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Exploration