MRPS33

Across TCGA pan-cancer cohorts, MRPS33 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of MRPS33’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where MRPS33 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MRPS33 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUAD, LIHC, and THCA are the cancer types where MRPS33 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPS33 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	+0.726	<.001	9	view →
LIHC	Male	II,III,IV	+0.802	<.001	8	view →
THCA	Male	All	−0.551	<.001	7	view →
BLCA	Female	III,IV	+0.451	.007	7	view →
LUSC	Female	All	+1.036	<.001	6	view →
BRCA	All	III,IV	+0.379	<.001	6	view →
COAD	All	II,III,IV	+0.362	<.001	6	view →
CHOL	Male	All	+1.054	<.001	3	view →
KIRC	Female	IV	+0.413	.004	3	view →
KIRP	All	II,III,IV	+0.356	.006	3	view →
HNSC	All	IV	+0.389	.023	2	view →
PRAD	All	All	+0.281	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

MRPS33–LUAD

Open the LUAD breakdown →