MRPS25

Across TCGA patient cohorts, MRPS25 protein abundance is significantly associated with the RNA expression of many other genes, with 17,926 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPS25-associated genes across cancer lineages are NEXN, AEBP1, and RASGRF2. Each is linked with MRPS25 in more than 7 cancer types. Because this analysis shows association rather than direction, both MRPS25-to-partner and partner-to-MRPS25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPS25 versus NEXN in OV, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS25→partner) and Y-score (partner→MRPS25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NEXN →	-1.178	-0.469	<.001	<.001	3	8
OV	AEBP1 →	-1.958	-0.437	<.001	.001	3	7
OV	RASGRF2 →	-0.882	-0.412	.001	.002	3	7
BRCA	DCN →	-1.148	-0.228	<.001	<.001	3	7
OV	C1R →	-0.949	-0.368	<.001	.004	3	7
OV	LHFPL6 →	-0.790	-0.358	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,926 associations by consensus.

MRPS25 vs NEXN — OV

Explore this scatter interactively →