Across TCGA patient cohorts, MRPS18B mutation is significantly associated with the RNA expression of many other genes, with 188 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPS18B-associated genes across cancer lineages are PPIAL4F, NCOR1P4, and ARL6IP1P1. Each is linked with MRPS18B in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPS18B-to-partner and partner-to-MRPS18B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS18B→partner) and Y-score (partner→MRPS18B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPIAL4F →	+0.068	+4.448	.005	.006	3	1
BRCA	NCOR1P4 →	+0.432	+4.540	.009	.009	3	1
BRCA	ARL6IP1P1 →	+0.061	+4.646	<.001	.008	3	1
BRCA	DUX4L47 →	+0.075	+6.234	<.001	<.001	3	1
BRCA	MREGP1 →	+0.349	+4.575	<.001	.009	3	1
CESC	OR1L4 →	+0.044	+4.812	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 188 associations by consensus.

Exploration

MRPS18B survival (RNA) · tumor vs normal (RNA) · all MRPS18B data types