Q-omics provides the consensus-scored DUX4L47 profile across patient tissues and cancer cell-line models. DUX4L47 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, DUX4L47 RNA expression shows 5,914 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight HNSC, and STAD as cancer lineages where DUX4L47 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes DUX4L47 survival associations across molecular data types. DUX4L47 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DUX4L47 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	8	HNSC (63)	view →

This table ranks reproducible DUX4L47 RNA expression–survival associations across cancer types. High DUX4L47 expression shows unfavorable associations in THYM, KIRP, OV and UCEC, but favorable associations in HNSC and SKCM. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .027). Together, the overview and detailed table identify HNSC as the clearest survival context for DUX4L47 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	II,III,IV	0.825	0.671	.027	63	view →
THYM	DFS	Tertile	II,III,IV	0.145	0.873	<.001	24	view →
KIRP	OS	Tertile	All	0.210	0.715	.005	24	view →
OV	DFS	Tertile	IV	0.125	0.476	.001	18	view →
UCEC	DFS	Tertile	All	0.405	0.681	.021	12	view →
SKCM	DFS	Tertile	All	0.844	0.610	.018	9	view →

Pink = unfavorable, green = favorable. all 8 lineages →

DUX4L47-HNSC (DFS)

Kaplan–Meier survival curve for DUX4L47 RNA expression in HNSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DUX4L47 in patient tissues and cancer cell lines. In patient samples, DUX4L47 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,914	STAD (5347)	view →
RNA	5,339	COAD (1993)	view →