Q-omics provides the consensus-scored MREGP1 profile across patient tissues and cancer cell-line models. MREGP1 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in THCA. Additionally, MREGP1 RNA expression shows 5,618 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight THCA, and STAD as cancer lineages where MREGP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MREGP1 survival associations across molecular data types. MREGP1 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MREGP1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	14	THCA (63)	view →

This table ranks reproducible MREGP1 RNA expression–survival associations across cancer types. High MREGP1 expression shows unfavorable associations in THCA, LUSC, OV, COAD, THYM and MESO. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for MREGP1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.586	0.952	<.001	63	view →
LUSC	OS	Tertile	All	0.423	0.740	.005	60	view →
OV	DFS	Tertile	IV	0.137	0.496	<.001	54	view →
COAD	OS	Tertile	III,IV	0.563	0.793	.003	51	view →
THYM	OS	Tertile	III,IV	0.229	1.000	<.001	39	view →
MESO	OS	Tertile	All	0.018	0.559	<.001	36	view →

Pink = unfavorable, green = favorable. all 14 lineages →

MREGP1-THCA (OS)

Kaplan–Meier survival curve for MREGP1 RNA expression in THCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MREGP1 in patient tissues and cancer cell lines. In patient samples, MREGP1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,618	STAD (5227)	view →
Protein (mass-spec)	2,945	LSCC (629)	view →