MREGP1

Across TCGA patient cohorts, MREGP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,618 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MREGP1-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, DNA conformation change, and Microtubule organizing center organization. Each is linked with MREGP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both MREGP1-to-partner and partner-to-MREGP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by MREGP1-low versus MREGP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MREGP1→partner) and Y-score (partner→MREGP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.076	+0.341	<.001	<.001	3	10
STAD	DNA conformation change →	+0.081	+0.322	<.001	<.001	3	10
STAD	Microtubule organizing center organization →	+0.071	+0.325	<.001	<.001	3	10
STAD	Mitotic spindle organization →	+0.087	+0.346	<.001	<.001	3	10
STAD	rRNA transcription →	+0.079	+0.308	<.001	<.001	3	10
STAD	Positive regulation of mitotic cell cycle →	+0.072	+0.280	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,618 associations by consensus.

Positive regulation of DNA metabolic process by MREGP1 expression — STAD

Explore this box plot interactively →