MRPS11

Across TCGA patient cohorts, MRPS11 protein abundance is significantly associated with the RNA expression of many other genes, with 13,429 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPS11-associated genes across cancer lineages are SSPN, DENND2A, and MAMDC2. Each is linked with MRPS11 in more than 4 cancer types. Because this analysis shows association rather than direction, both MRPS11-to-partner and partner-to-MRPS11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPS11 versus SSPN in OV, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPS11→partner) and Y-score (partner→MRPS11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SSPN →	-0.943	-0.295	.009	.004	3	5
OV	DENND2A →	-1.069	-0.379	<.001	<.001	3	5
UCEC	MAMDC2 →	-1.202	-0.257	.001	.003	3	5
BRCA	ZEB2 →	-0.719	-0.328	.001	<.001	3	5
UCEC	LSAMP →	-0.768	-0.235	.001	<.001	3	5
UCEC	LINC00702 →	-0.616	-0.224	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,429 associations by consensus.

MRPS11 vs SSPN — OV

Explore this scatter interactively →