MRPL41

Across TCGA cell cohorts, MRPL41 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,009 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPL41-associated GO terms across cancer lineages are CTP salvage, Energy coupled proton transmembrane transport, against electrochemical gradient, and Electron transport coupled proton transport. Each is linked with MRPL41 in more than 15 cancer types. Because this analysis shows association rather than direction, both MRPL41-to-partner and partner-to-MRPL41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTP salvage grouped by MRPL41-low versus MRPL41-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL41→partner) and Y-score (partner→MRPL41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	CTP salvage →	+0.155	+1.301	<.001	<.001	3	16
BONE	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.110	+1.506	.001	<.001	2	14
BONE	Electron transport coupled proton transport →	+0.110	+1.506	.001	<.001	2	14
LUNG_SCLC	Peptidyl-methionine modification →	+0.197	+0.752	.008	.002	3	13
PANCREAS	Regulation of mitochondrial DNA metabolic process →	+0.099	+1.233	<.001	<.001	3	12
BONE	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.240	+1.648	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,009 associations by consensus.

CTP salvage by MRPL41 expression — BONE

Explore this box plot interactively →