MRPL39

Across TCGA patient cohorts, MRPL39 protein abundance is significantly associated with the RNA expression of many other genes, with 16,349 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRPL39-associated genes across cancer lineages are MT-CO2, PPFIA2, and ADAMTS10. Each is linked with MRPL39 in more than 8 cancer types. Because this analysis shows association rather than direction, both MRPL39-to-partner and partner-to-MRPL39 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRPL39 versus MT-CO2 in HNSC, with a Pearson correlation of 0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL39→partner) and Y-score (partner→MRPL39) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MT-CO2 →	+1.027	+0.192	.001	.004	3	9
PDAC	PPFIA2 →	-0.630	-0.327	.001	<.001	3	8
UCEC	ADAMTS10 →	-0.764	-0.294	<.001	<.001	3	8
COAD	LMOD1 →	-1.126	-0.291	.002	.005	3	8
BRCA	TMEM119 →	-1.133	-0.359	<.001	<.001	3	8
BRCA	IFFO1 →	-0.626	-0.358	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,349 associations by consensus.

MRPL39 vs MT-CO2 — HNSC

Explore this scatter interactively →