MRPL37

Across TCGA patient cohorts, MRPL37 mutation is significantly associated with the RNA expression of many other genes, with 3,082 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MRPL37-associated genes across cancer lineages are TRBV24OR9-2, RN7SL822P, and RNA5SP419. Each is linked with MRPL37 in more than 1 cancer types. Because this analysis shows association rather than direction, both MRPL37-to-partner and partner-to-MRPL37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRBV24OR9-2 grouped by MRPL37-low versus MRPL37-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL37→partner) and Y-score (partner→MRPL37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	TRBV24OR9-2 →	+0.544	+4.882	<.001	.005	3	2
LUSC	RN7SL822P →	+0.148	+4.548	<.001	.009	3	2
LUSC	RNA5SP419 →	+1.034	+6.102	<.001	.001	3	2
LUSC	RNA5SP418 →	+0.859	+4.978	<.001	.005	3	2
LUSC	RNA5SP413 →	+1.745	+5.081	<.001	.004	3	2
LUSC	RNA5SP417 →	+1.247	+4.882	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,082 associations by consensus.

TRBV24OR9-2 by MRPL37 expression — LUSC

Explore this box plot interactively →