MRPL37

Across TCGA pan-cancer cohorts, MRPL37 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of MRPL37’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MRPL37 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MRPL37 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, LUAD, and HNSC are the cancer types where MRPL37 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MRPL37 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.931	<.001	11	view →
LUAD	Male	III,IV	+0.931	<.001	11	view →
HNSC	Male	All	+0.562	<.001	11	view →
STAD	Male	II,III,IV	+0.837	<.001	9	view →
BLCA	Female	All	+0.829	<.001	9	view →
KIRC	Female	III,IV	+0.594	<.001	9	view →
LUSC	Female	All	+1.425	<.001	8	view →
UCEC	All	III,IV	+0.714	.012	6	view →
BRCA	All	III,IV	+0.477	<.001	6	view →
LIHC	All	All	+0.383	<.001	5	view →
CHOL	All	All	+1.130	<.001	3	view →
READ	Female	All	+0.613	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

MRPL37–COAD

Open the COAD breakdown →