MRPL37

Across TCGA pan-cancer cohorts, MRPL37 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated MRPL37 data layer compared with 2 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MRPL37 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MRPL37 expression acts as an unfavorable survival marker, although some lineages such as COAD and STAD show a favorable association.

ACC, LIHC, and LGG are the cancer types where MRPL37 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.756	0.983	<.001	96	view →
LIHC	OS	Median	All	0.580	0.790	<.001	77	view →
LGG	DFS	Median	All	0.647	0.832	<.001	54	view →
COAD	OS	Median	All	0.678	0.473	.003	54	view →
SARC	DFS	Median	All	0.406	0.613	<.001	42	view →
STAD	DFS	Tertile	II,III,IV	0.616	0.378	<.001	40	view →
BLCA	OS	Quartile	All	0.498	0.656	.005	38	view →
KIRP	DFS	Quartile	All	0.839	0.961	.001	37	view →
SKCM	OS	Quartile	All	0.290	0.445	.001	34	view →
LAML	DFS	Quartile	All	0.388	0.683	.003	30	view →
MESO	DFS	Median	IV	0.175	0.485	.003	29	view →
UCEC	DFS	Median	All	0.790	0.884	<.001	28	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

MRPL37–ACC (OS)

Open the ACC breakdown →