MRPL37

Across TCGA cell cohorts, MRPL37 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,181 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MRPL37-associated GO terms across cancer lineages are DNA replication initiation, Mitotic spindle elongation, and Mitotic spindle midzone assembly. Each is linked with MRPL37 in more than 16 cancer types. Because this analysis shows association rather than direction, both MRPL37-to-partner and partner-to-MRPL37 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by MRPL37-low versus MRPL37-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MRPL37→partner) and Y-score (partner→MRPL37) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA replication initiation →	+0.191	+1.034	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Mitotic spindle elongation →	+0.260	+0.712	<.001	.001	3	16
LUNG_NSCLC_LUSC	Mitotic spindle midzone assembly →	+0.260	+0.712	<.001	.001	3	16
PANCREAS	Spindle elongation →	+0.326	+1.064	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Lagging strand elongation →	+0.140	+0.744	.002	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Nuclear pore localization →	+0.191	+1.337	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,181 associations by consensus.

DNA replication initiation by MRPL37 expression — PANCREAS

Explore this box plot interactively →