MRGBP

Across TCGA patient cohorts, MRGBP protein abundance is significantly associated with the RNA expression of many other genes, with 8,387 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MRGBP-associated genes across cancer lineages are CABLES2, ADNP, and MTG2. Each is linked with MRGBP in more than 5 cancer types. Because this analysis shows association rather than direction, both MRGBP-to-partner and partner-to-MRGBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MRGBP versus CABLES2 in LSCC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MRGBP→partner) and Y-score (partner→MRGBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CABLES2 →	+0.603	+0.293	<.001	<.001	3	6
GBM	ADNP →	+0.546	+0.394	<.001	<.001	3	5
BRCA	MTG2 →	+0.544	+0.471	.002	<.001	3	5
GBM	SMC4 →	+0.775	+0.338	.002	.001	3	5
GBM	TAF4 →	+0.515	+0.332	<.001	<.001	3	5
LSCC	GID8 →	+0.490	+0.255	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,387 associations by consensus.

MRGBP vs CABLES2 — LSCC

Explore this scatter interactively →