MPZL3

Across TCGA patient cohorts, MPZL3 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MPZL3-associated genes across cancer lineages are RN7SL163P, RNA5SP66, and PHKG1P3. Each is linked with MPZL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MPZL3-to-partner and partner-to-MPZL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL163P grouped by MPZL3-low versus MPZL3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPZL3→partner) and Y-score (partner→MPZL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL163P →	+0.145	+3.993	<.001	.005	3	2
BLCA	RNA5SP66 →	+0.278	+7.640	<.001	.009	3	1
SKCM	PHKG1P3 →	+0.150	+3.993	<.001	.005	3	1
SKCM	RPS23P4 →	+0.103	+4.564	<.001	.001	3	1
SKCM	RPL38P1 →	+0.210	+5.021	<.001	<.001	3	1
SKCM	RPS3AP31 →	+0.070	+4.683	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

RN7SL163P by MPZL3 expression — SKCM

Explore this box plot interactively →