Across TCGA patient cohorts, MPIG6B mutation is significantly associated with the RNA expression of many other genes, with 384 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MPIG6B-associated genes across cancer lineages are OSBPL9P3, MIR381, and MIR369. Each is linked with MPIG6B in more than 1 cancer types. Because this analysis shows association rather than direction, both MPIG6B-to-partner and partner-to-MPIG6B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MPIG6B→partner) and Y-score (partner→MPIG6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OSBPL9P3 →	+0.104	+2.620	.001	.004	3	2
BLCA	MIR381 →	+0.268	+7.640	<.001	.009	3	1
BLCA	MIR369 →	+0.963	+7.640	<.001	.009	3	1
BLCA	SNORD114-5 →	+0.628	+7.640	<.001	.009	3	1
BLCA	RNU6-624P →	+0.267	+7.640	<.001	.009	3	1
BLCA	MIR539 →	+0.633	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 384 associations by consensus.

Exploration

MPIG6B survival (RNA) · tumor vs normal (RNA) · all MPIG6B data types