MIR381

Q-omics provides the consensus-scored MIR381 profile across patient tissues and cancer cell-line models. MIR381 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in BLCA. Additionally, MIR381 RNA expression shows 9,604 significant gene co-expression associations, with the highest sampling consensus in BRCA. Together, these results highlight BLCA, and BRCA as cancer lineages where MIR381 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes MIR381 survival associations across molecular data types. MIR381 RNA expression shows survival associations in the most cancer types (8), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MIR381 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	8	BLCA (45)	view →
Mutation	Kaplan–Meier	1	SKCM (9)	view →

This table ranks reproducible MIR381 RNA expression–survival associations across cancer types. High MIR381 expression shows unfavorable associations in BLCA, ACC, PAAD, STAD and LGG, but favorable associations in LAML. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for MIR381 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.127	0.627	<.001	45	view →
ACC	DFS	Tertile	All	0.226	0.765	<.001	39	view →
PAAD	OS	Tertile	All	0.155	0.596	<.001	36	view →
STAD	OS	Tertile	IV	0.052	0.496	<.001	36	view →
LAML	DFS	Tertile	All	1.000	0.339	.002	36	view →
LGG	OS	Tertile	All	0.415	0.803	<.001	21	view →

Pink = unfavorable, green = favorable. all 8 lineages →

MIR381-BLCA (DFS)

Explore this curve interactively →