Across TCGA patient cohorts, MIR381 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIR381-associated genes across cancer lineages are RNU6-1208P, RNU6-956P, and PMS2P11. Each is linked with MIR381 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR381-to-partner and partner-to-MIR381 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR381→partner) and Y-score (partner→MIR381) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1208P →	+0.369	+4.622	<.001	.001	3	1
SKCM	RNU6-956P →	+1.329	+4.884	<.001	.004	3	1
SKCM	PMS2P11 →	+0.101	+3.661	<.001	.009	3	1
SKCM	ZNF519P4 →	+0.346	+4.282	<.001	.009	3	1
SKCM	PCDH20 →	+0.255	+3.926	.008	.007	3	1
SKCM	TBC1D3I →	+0.021	+3.838	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

MIR381 survival (RNA) · tumor vs normal (RNA) · all MIR381 data types