Q-omics provides the consensus-scored MIR539 profile across patient tissues and cancer cell-line models. MIR539 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in PAAD. Additionally, MIR539 RNA expression shows 11,566 significant gene co-expression associations, with the highest sampling consensus in BRCA. Together, these results highlight PAAD, and BRCA as cancer lineages where MIR539 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MIR539 survival associations across molecular data types. MIR539 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MIR539 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	PAAD (72)	view →

This table ranks reproducible MIR539 RNA expression–survival associations across cancer types. High MIR539 expression shows unfavorable associations in PAAD, BLCA, CHOL, UCEC and PCPG, but favorable associations in ESCA. The PAAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify PAAD as the clearest survival context for MIR539 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	OS	Tertile	All	0.112	0.613	<.001	72	view →
BLCA	DFS	Tertile	All	0.127	0.627	<.001	45	view →
CHOL	DFS	Tertile	All	0.045	0.486	.009	45	view →
UCEC	DFS	Tertile	II,III,IV	0.096	0.511	.034	24	view →
ESCA	OS	Tertile	III,IV	1.000	0.366	.019	18	view →
PCPG	DFS	Tertile	All	0.576	0.940	<.001	18	view →

Pink = unfavorable, green = favorable. all 9 lineages →

MIR539-PAAD (OS)

Kaplan–Meier survival curve for MIR539 RNA expression in PAAD: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MIR539 in patient tissues and cancer cell lines. In patient samples, MIR539 shows the broadest associations at the RNA and protein expression levels, with BRCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	11,566	BRCA (4950)	view →
Protein (mass-spec)	4,422	UCEC (1531)	view →
▼Mutation
RNA	22	SKCM (18)	view →