MORN1

Across TCGA patient cohorts, MORN1 mutation is significantly associated with the RNA expression of many other genes, with 3,122 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MORN1-associated genes across cancer lineages are SRCIN1, MRFAP1, and PTP4A3. Each is linked with MORN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MORN1-to-partner and partner-to-MORN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SRCIN1 grouped by MORN1-low versus MORN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MORN1→partner) and Y-score (partner→MORN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SRCIN1 →	-0.681	-2.247	.001	.002	3	2
COAD	MRFAP1 →	+0.485	+3.210	<.001	.009	3	2
UCEC	PTP4A3 →	-0.759	-2.689	.001	.005	3	2
UCEC	BRI3BP →	+0.843	+2.747	<.001	<.001	3	2
UCEC	RPS27L →	+0.619	+3.721	<.001	<.001	3	2
UCEC	JPT1 →	+0.463	+1.847	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,122 associations by consensus.

SRCIN1 by MORN1 expression — UCEC

Explore this box plot interactively →