MORN1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, MORN1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of MORN1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where MORN1 RNA is repressed in tumor relative to normal tissue. In most cancer types MORN1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and COAD are the cancer types where MORN1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MORN1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHFemaleAll−1.371<.00111view →
THCAMaleIII,IV−0.672<.00110view →
COADAllII,III,IV+0.302<.0019view →
STADMaleII,III,IV+0.562.0014view →
BRCAAllAll+0.222.0064view →
LIHCAllAll+0.187<.0014view →
CHOLAllAll+0.644<.0013view →
UCECAllAll−0.636.0112view →
KIRCFemaleAll+0.217.0121view →
READAllAll+0.193.0401view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

MORN1–KICH

Tumor-vs-normal expression box plot for MORN1 RNA in KICH.

Open the KICH breakdown →

Exploration