MON1B

Across TCGA patient cohorts, MON1B RNA expression is significantly associated with the mutation status of many other genes, with 12,429 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MON1B-associated genes across cancer lineages are TTN, TP53, and RYR2. Each is linked with MON1B in more than 3 cancer types. Because this analysis shows association rather than direction, both MON1B-to-partner and partner-to-MON1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TTN grouped by MON1B-low versus MON1B-high in READ.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MON1B→partner) and Y-score (partner→MON1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	TTN →	+2.051	+0.270	<.001	<.001	3	4
GBM	TP53 →	+1.716	+0.253	.004	.007	2	4
READ	RYR2 →	+3.282	+0.334	.005	.001	3	3
STAD	KMT2D →	+2.857	+0.267	.001	.005	3	3
UCEC	APC →	+1.478	+0.386	<.001	<.001	3	3
UCEC	ATP8B4 →	+1.879	+0.503	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,429 associations by consensus.

TTN by MON1B expression — READ

Explore this box plot interactively →