Across TCGA patient cohorts, MOG protein abundance is significantly associated with the RNA expression of many other genes, with 2,427 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MOG-associated genes across cancer lineages are LDLRAP1, MVK, and INHBA. Each is linked with MOG in more than 1 cancer types. Because this analysis shows association rather than direction, both MOG-to-partner and partner-to-MOG results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOG→partner) and Y-score (partner→MOG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LDLRAP1 →	+0.587	+1.414	<.001	<.001	3	2
CCRCC	MVK →	-0.936	-0.597	.009	.004	3	1
CCRCC	INHBA →	+1.066	+0.468	.007	.006	3	1
CCRCC	SIX1 →	+0.732	+0.782	.004	.001	3	1
CCRCC	DLG4 →	+0.363	+0.554	.006	.001	3	1
CCRCC	C7orf69 →	+0.390	+0.515	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,427 associations by consensus.

Exploration

MOG survival (RNA) · tumor vs normal (RNA) · all MOG data types