MOB2

Across TCGA patient cohorts, MOB2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,920 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MOB2-associated genes across cancer lineages are CPED1, CDC6, and TIMM10B. Each is linked with MOB2 in more than 6 cancer types. Because this analysis shows association rather than direction, both MOB2-to-partner and partner-to-MOB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MOB2 versus CPED1 in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOB2→partner) and Y-score (partner→MOB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CPED1 →	+0.826	+0.209	.001	.009	3	7
UCEC	CDC6 →	-0.994	-0.277	<.001	<.001	3	7
OV	TIMM10B →	+0.430	+0.265	<.001	<.001	3	6
COAD	SYNPO2 →	+1.598	+0.254	<.001	<.001	3	6
CCRCC	PRKG1 →	+0.670	+0.115	<.001	<.001	3	6
UCEC	CENPM →	-0.913	-0.161	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,920 associations by consensus.

MOB2 vs CPED1 — BRCA

Explore this scatter interactively →