MOB1A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MOB1A mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MOB1A-associated genes across cancer lineages are Basophils. Each is linked with MOB1A in more than 1 cancer types. Because this analysis shows association rather than direction, both MOB1A-to-partner and partner-to-MOB1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basophils grouped by MOB1A-low versus MOB1A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MOB1A→partner) and Y-score (partner→MOB1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECBasophils →+0.245+3.169.008.02031
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Basophils by MOB1A expression — UCEC

Box plot of Basophils in MOB1A-low vs MOB1A-high samples in UCEC.

Explore this box plot interactively →

Exploration