MOB1A

Across TCGA cell cohorts, MOB1A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,187 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MOB1A-associated GO terms across cancer lineages are Regulation of mitotic cytokinesis, Protein localization to chromosome, and Negative regulation of cell cycle process. Each is linked with MOB1A in more than 14 cancer types. Because this analysis shows association rather than direction, both MOB1A-to-partner and partner-to-MOB1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic cytokinesis grouped by MOB1A-low versus MOB1A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MOB1A→partner) and Y-score (partner→MOB1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of mitotic cytokinesis →	+0.125	+0.578	<.001	.001	3	15
LARGE_INTESTINE	Protein localization to chromosome →	+0.087	+0.567	<.001	<.001	3	14
LARGE_INTESTINE	Negative regulation of cell cycle process →	+0.062	+0.547	<.001	<.001	3	13
BREAST	Negative regulation of mitotic cell cycle phase transition →	+0.063	+0.524	.001	.003	3	13
KIDNEY	Regulation of chromosome separation →	+0.123	+0.595	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via nonhomologous end joining →	+0.068	+0.843	.001	.003	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,187 associations by consensus.

Regulation of mitotic cytokinesis by MOB1A expression — BREAST

Explore this box plot interactively →