MNX1

Across TCGA cell cohorts, MNX1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MNX1-associated genes across cancer lineages are OR51T1, GSG1L2, and TBC1D3. Each is linked with MNX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MNX1-to-partner and partner-to-MNX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51T1 grouped by MNX1-low versus MNX1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MNX1→partner) and Y-score (partner→MNX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1
LARGE_INTESTINE	TBC1D3 →	+0.123	+4.273	<.001	.006	3	1
SKIN	CLEC4C →	+0.067	+4.977	<.001	.007	3	1
SKIN	PRSS58 →	+0.047	+4.977	<.001	.007	3	1
BLOOD_Lymphoma	SELE →	+0.031	+4.350	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

OR51T1 by MNX1 expression — BLOOD_Leukemia

Explore this box plot interactively →