MNX1-AS2

Across TCGA pan-cancer cohorts, MNX1-AS2 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated MNX1-AS2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MNX1-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MNX1-AS2 expression acts as an unfavorable survival marker, although some lineages such as CHOL and SKCM show a favorable association.

KIRC, DLBC, and ACC are the cancer types where MNX1-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.530	0.719	<.001	114	view →
DLBC	DFS	Median	III,IV	0.266	0.885	.003	43	view →
ACC	DFS	Quartile	All	0.479	0.745	.008	33	view →
KIRP	DFS	Quartile	All	0.489	0.844	.004	29	view →
KICH	DFS	Median	All	0.700	1.000	.003	28	view →
MESO	DFS	Quartile	III,IV	0.235	0.464	.012	26	view →
UCEC	DFS	Quartile	IV	0.294	0.744	.021	24	view →
CHOL	OS	Median	All	0.892	0.178	.002	18	view →
SKCM	DFS	Quartile	IV	0.943	0.093	.014	18	view →
HNSC	DFS	Quartile	All	0.507	0.657	.003	15	view →
ESCA	OS	Median	All	0.647	1.000	.015	15	view →
BRCA	OS	Tertile	III,IV	0.444	0.679	.023	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

MNX1-AS2–KIRC (DFS)

Open the KIRC breakdown →