MNX1-AS2

Across TCGA pan-cancer cohorts, MNX1-AS2 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of MNX1-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where MNX1-AS2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MNX1-AS2 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

KIRP, BLCA, and STAD are the cancer types where MNX1-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MNX1-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	II,III,IV	+0.860	<.001	11	view →
BLCA	Male	All	+1.575	<.001	8	view →
STAD	Female	All	+1.567	<.001	8	view →
LUAD	Female	All	+1.186	<.001	8	view →
COAD	Male	II,III,IV	+0.933	<.001	8	view →
KIRC	All	All	+0.170	<.001	7	view →
UCEC	All	III,IV	+1.657	<.001	6	view →
BRCA	All	All	+0.469	<.001	4	view →
CHOL	Female	All	+2.796	<.001	3	view →
LIHC	Female	All	+0.410	.026	3	view →
PRAD	All	All	+1.162	<.001	2	view →
READ	Female	All	+1.023	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

MNX1-AS2–KIRP

Open the KIRP breakdown →