MMP26

Across TCGA cell cohorts, MMP26 RNA expression is significantly associated with the go_rna of many other GO terms, with 519 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible MMP26-associated GO terms across cancer lineages are Notch signaling pathway, Putrescine transport, and Cell fate specification. Each is linked with MMP26 in more than 1 cancer types. Because this analysis shows association rather than direction, both MMP26-to-partner and partner-to-MMP26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch signaling pathway grouped by MMP26-low versus MMP26-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP26→partner) and Y-score (partner→MMP26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Notch signaling pathway →	+0.082	+1.024	<.001	<.001	3	2
LUNG_SCLC	Putrescine transport →	+0.149	+0.683	<.001	<.001	3	2
LUNG_SCLC	Cell fate specification →	+0.093	+1.008	<.001	<.001	3	2
LUNG_SCLC	Regulation of exocytosis →	+0.058	+0.678	.001	.004	3	2
LUNG_SCLC	Short-term synaptic potentiation →	+0.709	+0.789	.003	.005	3	2
LUNG_SCLC	Response to molecule of bacterial origin →	-0.043	-0.614	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 519 associations by consensus.

Notch signaling pathway by MMP26 expression — LUNG_SCLC

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