MMP26

Across TCGA cell cohorts, MMP26 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible MMP26-associated genes across cancer lineages are OR13C4 and SMIM36. Each is linked with MMP26 in more than 1 cancer types. Because this analysis shows association rather than direction, both MMP26-to-partner and partner-to-MMP26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13C4 grouped by MMP26-low versus MMP26-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP26→partner) and Y-score (partner→MMP26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR13C4 →	+0.165	+5.029	<.001	.006	3	2
OVARY	SMIM36 →	+0.046	+4.228	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR13C4 by MMP26 expression — LUNG_SCLC

Explore this box plot interactively →