MMP24

Across TCGA patient cohorts, MMP24 mutation is significantly associated with the RNA expression of many other genes, with 1,143 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MMP24-associated genes across cancer lineages are LINC02845, RNU4-88P, and MIR549A. Each is linked with MMP24 in more than 2 cancer types. Because this analysis shows association rather than direction, both MMP24-to-partner and partner-to-MMP24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02845 grouped by MMP24-low versus MMP24-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP24→partner) and Y-score (partner→MMP24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02845 →	+0.055	+3.897	<.001	.009	3	3
ESCA	RNU4-88P →	+0.458	+5.681	<.001	.003	3	2
COAD	MIR549A →	+0.423	+3.271	.009	.009	3	2
COAD	RNU11-3P →	+0.480	+3.011	<.001	.009	3	2
COAD	PLA2G12AP2 →	+0.096	+4.225	<.001	.007	3	2
COAD	MIR3672 →	+0.434	+5.831	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,143 associations by consensus.

LINC02845 by MMP24 expression — SKCM

Explore this box plot interactively →