MMP21

Across TCGA patient cohorts, MMP21 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,168 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MMP21-associated proteins across cancer lineages are CTBP2, LMNB2, and VEZF1. Each is linked with MMP21 in more than 4 cancer types. Because this analysis shows association rather than direction, both MMP21-to-partner and partner-to-MMP21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MMP21 versus CTBP2 in GBM, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP21→partner) and Y-score (partner→MMP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CTBP2 →	+0.307	+0.292	<.001	<.001	3	5
OV	LMNB2 →	+0.331	+0.376	.007	.002	3	5
BRCA	VEZF1 →	+0.398	+0.339	<.001	<.001	3	4
BRCA	S100A9 →	-1.037	-0.459	.002	<.001	3	4
BRCA	DDAH1 →	+0.542	+0.371	<.001	<.001	3	4
BRCA	MMP2 →	+0.580	+0.392	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,168 associations by consensus.

MMP21 vs CTBP2 — GBM

Explore this scatter interactively →