MMP20

Across TCGA patient cohorts, MMP20 mutation is significantly associated with the RNA expression of many other genes, with 1,377 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MMP20-associated genes across cancer lineages are RNU7-113P, COX6CP7, and TGIF1P1. Each is linked with MMP20 in more than 2 cancer types. Because this analysis shows association rather than direction, both MMP20-to-partner and partner-to-MMP20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-113P grouped by MMP20-low versus MMP20-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP20→partner) and Y-score (partner→MMP20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU7-113P →	+0.538	+3.991	<.001	<.001	3	3
UCEC	COX6CP7 →	+0.128	+2.097	.009	.005	3	3
SKCM	TGIF1P1 →	+0.056	+2.498	<.001	.007	3	3
SKCM	RDXP2 →	+0.197	+3.284	<.001	.002	3	2
SKCM	LINC00571 →	+0.600	+3.207	<.001	.009	3	2
SKCM	SNRPD2P2 →	+0.134	+2.885	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,377 associations by consensus.

RNU7-113P by MMP20 expression — HNSC

Explore this box plot interactively →