MMP13

Across TCGA patient cohorts, MMP13 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,047 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MMP13-associated proteins across cancer lineages are KIF20B_S1740, KMT2B_S351, and LAMB1. Each is linked with MMP13 in more than 3 cancer types. Because this analysis shows association rather than direction, both MMP13-to-partner and partner-to-MMP13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MMP13 versus KIF20B_S1740 in LSCC, with a Pearson correlation of -0.37.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP13→partner) and Y-score (partner→MMP13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KIF20B_S1740 →	-0.789	-1.359	<.001	<.001	3	3
LSCC	KMT2B_S351 →	-0.493	-1.074	<.001	<.001	3	3
BRCA	LAMB1 →	+0.466	+0.884	<.001	<.001	3	3
LSCC	LGALS1 →	+0.420	+1.287	<.001	<.001	3	3
BRCA	LRP1 →	+0.429	+0.834	<.001	<.001	3	3
BRCA	LRRC17 →	+0.956	+0.965	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,047 associations by consensus.

MMP13 vs KIF20B_S1740 — LSCC

Explore this scatter interactively →