MMEL1

Across TCGA cell cohorts, MMEL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,577 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MMEL1-associated GO terms across cancer lineages are Regulation of tolerance induction dependent upon immune response, Anterograde dendritic transport of neurotransmitter receptor complex, and Regulation of hippocampal neuron apoptotic process. Each is linked with MMEL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both MMEL1-to-partner and partner-to-MMEL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of tolerance induction dependent upon immune response grouped by MMEL1-low versus MMEL1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MMEL1→partner) and Y-score (partner→MMEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of tolerance induction dependent upon immune response →	+1.320	+2.320	.002	<.001	3	8
SKIN	Anterograde dendritic transport of neurotransmitter receptor complex →	+0.086	+0.529	.007	.001	3	7
OVARY	Regulation of hippocampal neuron apoptotic process →	+1.521	+1.281	<.001	<.001	3	7
URINARY_TRACT	Regulation of endoplasmic reticulum unfolded protein response →	+0.102	+1.547	.001	<.001	3	7
PANCREAS	Positive regulation of IRE1-mediated unfolded protein response →	+0.095	+1.832	<.001	<.001	3	7
LARGE_INTESTINE	Negative regulation of myeloid leukocyte mediated immunity →	+1.678	+1.014	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,577 associations by consensus.

Regulation of tolerance induction dependent upon immune response by MMEL1 expression — URINARY_TRACT

Explore this box plot interactively →