MIR7-3HG

Across TCGA patient cohorts, MIR7-3HG mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR7-3HG-associated genes across cancer lineages are H3-2, RN7SL650P, and MIR593. Each is linked with MIR7-3HG in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR7-3HG-to-partner and partner-to-MIR7-3HG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H3-2 grouped by MIR7-3HG-low versus MIR7-3HG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR7-3HG→partner) and Y-score (partner→MIR7-3HG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	H3-2 →	+0.324	+3.871	.003	.004	3	1
UCEC	RN7SL650P →	+0.483	+3.681	.003	.007	3	1
UCEC	MIR593 →	+0.705	+3.794	.009	.005	3	1
UCEC	PHBP13 →	+0.317	+3.841	<.001	.005	3	1
UCEC	IGHD1-1 →	+1.229	+4.335	<.001	.007	3	1
UCEC	IGKV2D-30 →	+0.791	+3.792	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

H3-2 by MIR7-3HG expression — UCEC

Explore this box plot interactively →