MIR7-3HG

Across TCGA pan-cancer cohorts, MIR7-3HG RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated MIR7-3HG data layer compared with 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MIR7-3HG RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR7-3HG expression acts as an unfavorable survival marker, although some lineages such as CESC and ACC show a favorable association.

UCEC, KIRC, and CESC are the cancer types where MIR7-3HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	0.764	0.876	<.001	62	view →
KIRC	OS	Median	All	0.541	0.697	<.001	34	view →
CESC	OS	Median	All	0.760	0.426	<.001	32	view →
KICH	DFS	Tertile	All	0.700	0.954	.001	32	view →
THCA	DFS	Tertile	III,IV	0.836	0.968	.003	31	view →
ACC	DFS	Median	IV	0.594	0.151	.003	24	view →
READ	DFS	Quartile	II,III,IV	0.258	0.758	.004	21	view →
UVM	OS	Median	All	0.707	0.979	.006	20	view →
BLCA	OS	Tertile	II,III,IV	0.690	0.568	.022	19	view →
UCS	OS	Quartile	All	0.474	0.806	.010	18	view →
PAAD	DFS	Tertile	All	0.521	0.244	.007	17	view →
LGG	DFS	Tertile	All	0.577	0.399	.002	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

MIR7-3HG–UCEC (DFS)

Open the UCEC breakdown →