MIR7-3HG

Across TCGA pan-cancer cohorts, MIR7-3HG RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of MIR7-3HG’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MIR7-3HG RNA is repressed in tumor relative to normal tissue. In most cancer types MIR7-3HG is over-expressed in tumor, although a few such as COAD and STAD show the opposite, repressed pattern.

COAD, BRCA, and STAD are the cancer types where MIR7-3HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR7-3HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	All	−0.303	<.001	8	view →
BRCA	Female	All	+0.165	.022	4	view →
STAD	Male	IV	−0.445	.020	3	view →
HNSC	All	All	+0.047	.026	3	view →
KIRC	Male	III,IV	+0.028	.020	3	view →
READ	All	All	−0.390	.002	2	view →
KICH	All	IV	+0.040	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

MIR7-3HG–COAD

Open the COAD breakdown →