MIR6859-1

Across TCGA patient cohorts, MIR6859-1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR6859-1-associated genes across cancer lineages are RNU6-208P, SNORD74B, and MT1CP. Each is linked with MIR6859-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR6859-1-to-partner and partner-to-MIR6859-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-208P grouped by MIR6859-1-low versus MIR6859-1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR6859-1→partner) and Y-score (partner→MIR6859-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-208P →	+0.668	+4.578	.001	.004	3	1
UCEC	SNORD74B →	+0.504	+4.551	<.001	.009	3	1
UCEC	MT1CP →	+0.791	+4.871	<.001	.002	3	1
UCEC	RN7SL152P →	+0.293	+4.719	.001	.003	3	1
UCEC	RN7SL215P →	+0.213	+4.694	.001	.007	3	1
UCEC	RN7SL308P →	+0.429	+4.778	.005	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

RNU6-208P by MIR6859-1 expression — UCEC

Explore this box plot interactively →